Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells
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چکیده
منابع مشابه
Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells
Glucagon like peptide-1 is an insulinotropic hormone released from intestinal L-cells in response to food ingestion. Here, we investigated mechanisms underlying the sensing of peptones by primary small intestinal L-cells. Meat, casein and vegetable-derived peptones (5 mg/ml), the L-amino acids Phe, Trp, Gln and Ala (20 mM each), and the dipeptide glycine-sarcosine (20 mM) stimulated GLP-1 secre...
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ژورنال
عنوان ژورنال: Peptides
سال: 2016
ISSN: 0196-9781
DOI: 10.1016/j.peptides.2015.07.019